The Carter Family finds itself in serious financial difficulty when its patriarch, druggist Doc Carter (Frank Craven), is all but forced out of business by a neighboring chain store. Doc isn't worried so much for himself and his wife Emma (Fay Bainter) as he is for his five children, played by Scotty Beckett, Bennie Bartlett, Donald Brenon, Mary Thomas and Gloria Carter (who real name is the same as her "reel" name). But there may be a way out: wealthy Bill and Gloria Hastings (Edmund Lowe, Genevieve Tobin), longtime friends of the Carters, have offered to adopt the couple's polio-stricken son Dickie (Beckett) for a substantial fee. Doc and Emma refuse this offer, but their somewhat more practical children offer themselves up for adoption rather than separate little Dickie from his parents. The ultimately happy denoument suggests that Paramount Pictures hoped to develop a "Carter Family" series, though no such project developed.